ESTP Expert Workshop
Monday 22 September 2025
The ESTP International Expert Workshop will be organized in the Hilton Deansgate Hotel in Manchester.
303 Deansgate
Manchester M3 4LQ
United Kingdom
W: Hilton Manchester Deansgate | Central Manchester
Adversity determination of female reproductive findings in animals and significance for humans
The topic of the 11th ESTP International Expert Workshop, which will take place on September 22nd, 2025, in Manchester, UK will be “Adversity determination of female reproductive findings in animals and significance for humans.” The workshop was prepared by a group of 21 experts from diverse backgrounds in toxicopathology, clinical pathology, reproductive toxicology as well as regulatory toxicology.
The workshop will start with a review of adversity determination in nonclinical toxicology studies, to set the stage for a more focused discussion on the challenges of determining adversity in the female reproductive system. The resulting guiding principles for adversity determination will be then summarized.
Further presentations will discuss the translatability to humans, including overall assessment of female fertility risk throughout development and factors which may contribute to it, such as e.g. therapeutic indication and mode of action. Also, the differences between pharmaceutical and agrochemical regulatory environment will be highlighted. The talks will be intermingled with interactive case presentations with audience participation by an electronic voting system.
The workshop will end with an open discussion between the audience and experts, after which conclusions and recommendations for adversity determination of female reproductive findings in animal toxicology studies and integrated reproductive risk assessment will be summarized.
PROGRAM
08.20 – 08.30 | Welcome and Introduction
08.30 – 08.50 Current Definition of Adversity | Daniel Patrick & Sean Troth
08.50 – 09.20 | Problem Statement presented with case studies | Justin Vidal
09.20 – 10.10 | Morning Coffee Break
10.10 - 12.30 | Panel Discussion 1 - Challenges of Adversity Determination for the Female Reproductive System at the Study Level | Pragati Coder
12.30 – 13.30 | Lunch
13.30 – 15.30 | Panel Discussion 2 - Communication of Adversity for the Female Reproductive System at the Program Level | Bernd Baier
15.30 – 15.50 | Afternoon Coffee Break
15.50 – 17.20 | Workshop Experts and Audience Panel - Future Recommendations and Proposed Definition of Adversity for the Female Reproductive System | Roger Alison
17.20 - 17.30 | Closing Remarks | Emmanuelle Balme
17.30 | End of workshop
The expert panel of the ESTP Expert Workshop
Roger Alison
Ute Bach
Bernd Baier
Emmanuelle Balme
Christopher Bowman
Pragati Coder
Eveline De Rijk
Beth Dray
Laetitia Elies
Johannes Harleman
Doris Hoeschele
Maike Huisinga
Monika Keresztes
Heike Marxfeld
Luann Mckinney
Daniel Patrick
Nicole Principato
Mikala Skydsgaard
Sean Troth
Jan Willem Van der Laan
Justin Vidal
Registration fee
Early fee on or before 22 June 2025
ESTP member - Early Bird Fee: € 195.00
ESTP member - Late Fee: € 210.00
Non-member - Early Bird Fee: € 210.00
Non-member - Late Fee: € 230.00
Prices are incl. 20% UK VAT
The registration fee includes
• Admission to the Expert Workshop
• Coffee breaks
• Lunch
How to register
In order to register for the Expert Meeting and / or the BSTP/ESTP congress please register online and be sure to submit your registration. Upon receipt of your completed registration form and payment, you will receive an email confirmation of your registration.