IATP satellite symposium
Tuesday 23 September 2025
09.00 - 13.00 hrs
The IATP Symposium will be organized in the Hilton Deansgate Hotel in Manchester.
303 Deansgate
Manchester M3 4LQ
United Kingdom
W: Hilton Manchester Deansgate | Central Manchester
Pathology Working Groups (PWG) in Toxicologic Pathology
Pathology Working Groups (PWG) are specialized panels of expert pathologists convened to provide independent, unbiased assessments of specific questions that arise during pathology peer review or presented by regulatory authorities. PWGs play a crucial role in establishing appropriate nomenclature and diagnostic criteria for pathology findings of interest or novel findings, as well as addressing issues that may result in a clinical hold on candidate compounds. PWGs are routinely conducted by the U.S. National Toxicology Program (NTP) for rodent carcinogenicity studies in environmental chemical hazard identification and risk assessment. The 2025 International Academy of Toxicologic Pathology (IATP) Satellite Symposium will provide historical perspectives and context with current applications of PWGs and modified PWGs in risk assessment for environmental chemicals and pharmaceuticals. Key topics will include:
- Background and historical perspectives of PWGs at NTP/DTT/NIEHS
- A comparison of PWGs in the chemical industry and pharmaceutical sector.
- The evolution and application of Expert Working Panel (EWP)
- Regulatory perspectives from FDA and other regulatory agencies.
- Panel discussion featuring experts from pharmaceutical and chemical industry, academia/government organizations, contract research organizations (CROs), and regulatory agencies.
This symposium will provide valuable insights into the role of PWGs in toxicologic pathology and their impact on risk assessment and regulatory decision-making.
Program Outline: 9 am to 1 pm
Moderators: Heike-Antje Markfeld and Doug Wolf
|
Tentative Time |
Name of the Speaker and Presentation Topic |
|
9.00-9.10 am |
Welcome and Introduction (IATP Education Committee) (10 min) |
|
9.10-9.55 am
|
Dr. Mark Cesta., NIEHS, Research Triangle Park, NC, USA (45 min) Presentation: The Peer Review Process in the Division of Translational Toxicology (DTT) and the U.S. National Toxicology Program (NTP). |
|
9.55-10.40 am
|
Dr. Paul Snyder., Experimental Pathology Laboratories Inc., (EPL), USA (45 min) Presentation: Pathology Working Groups: Reviews to Address Specific Scientific and/or Regulatory Issues. |
|
10.40-11.10 am |
Coffee Break (30 min) |
|
11.10-11.40 am
|
Dr. Maurice Cary., Pathology Experts GmbH, Switzerland (30 min) Presentation: Expert Working Panel (EWP)- a Modified PWG: Confirming the Morphologic Diagnosis is Only the First Step. |
|
11.40-12.10 pm
|
Dr. Frederic Schorsch, Bayer S.A.S, France(30 min) Presentation: PWG - Perspectives from the Agrochemical Realm. |
|
12.10-12.55 pm |
Panel Discussion (45 minutes) |
|
12.55-1.00 pm |
Closing Remarks (IATP Education Committee) (5 min) |
|
1.00-2.00 pm |
Lunch |
Registration fee
IATP Symposium € 205.00
Prices are incl. 20% UK VAT
The registration fee includes
• Admission to the IATP scientific sessions
• Coffee break
• Lunch
How to register
In order to register for the IATP Symposium and / or the BSTP/ESTP congress please register online and be sure to submit your registration. Upon receipt of your completed registration form and payment, you will receive an email confirmation of your registration.
REGISTER HERE